LOC101164305 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC101164305

Nuclear receptor subfamily 2, group E, member 3. (415 aa)

Predicted Functional Partners:

LOC105353878

0.690

otx2

0.678

kdm1a

0.671

LOC101175558

0.668

rere

0.668

atn1

0.668

med1

0.646

ncor1

0.591

ncor2

0.591

LOC101158106

0.590

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101158106	LOC101164305	ENSORLP00000007558	ENSORLP00000009000	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.	Nuclear receptor subfamily 2, group E, member 3.	0.590
LOC101164305	LOC101158106	ENSORLP00000009000	ENSORLP00000007558	Nuclear receptor subfamily 2, group E, member 3.	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.	0.590
LOC101164305	LOC101175558	ENSORLP00000009000	ENSORLP00000002362	Nuclear receptor subfamily 2, group E, member 3.	Arginine-glutamic acid dipeptide (RE) repeats b.	0.668
LOC101164305	LOC105353878	ENSORLP00000009000	ENSORLP00000002498	Nuclear receptor subfamily 2, group E, member 3.	Neural retina leucine zipper.	0.690
LOC101164305	atn1	ENSORLP00000009000	ENSORLP00000029951	Nuclear receptor subfamily 2, group E, member 3.	Atrophin 1.	0.668
LOC101164305	kdm1a	ENSORLP00000009000	ENSORLP00000015788	Nuclear receptor subfamily 2, group E, member 3.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.671
LOC101164305	med1	ENSORLP00000009000	ENSORLP00000043584	Nuclear receptor subfamily 2, group E, member 3.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.646
LOC101164305	ncor1	ENSORLP00000009000	ENSORLP00000015017	Nuclear receptor subfamily 2, group E, member 3.	Nuclear receptor corepressor 1.	0.591
LOC101164305	ncor2	ENSORLP00000009000	ENSORLP00000017559	Nuclear receptor subfamily 2, group E, member 3.	Nuclear receptor corepressor 2.	0.591
LOC101164305	otx2	ENSORLP00000009000	ENSORLP00000037058	Nuclear receptor subfamily 2, group E, member 3.	Homeobox domain-containing protein.	0.678
LOC101164305	rere	ENSORLP00000009000	ENSORLP00000007033	Nuclear receptor subfamily 2, group E, member 3.	Arginine-glutamic acid dipeptide (RE) repeats a.	0.668
LOC101175558	LOC101164305	ENSORLP00000002362	ENSORLP00000009000	Arginine-glutamic acid dipeptide (RE) repeats b.	Nuclear receptor subfamily 2, group E, member 3.	0.668
LOC105353878	LOC101164305	ENSORLP00000002498	ENSORLP00000009000	Neural retina leucine zipper.	Nuclear receptor subfamily 2, group E, member 3.	0.690
atn1	LOC101164305	ENSORLP00000029951	ENSORLP00000009000	Atrophin 1.	Nuclear receptor subfamily 2, group E, member 3.	0.668
kdm1a	LOC101164305	ENSORLP00000015788	ENSORLP00000009000	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Nuclear receptor subfamily 2, group E, member 3.	0.671
med1	LOC101164305	ENSORLP00000043584	ENSORLP00000009000	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 2, group E, member 3.	0.646
med1	ncor1	ENSORLP00000043584	ENSORLP00000015017	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.686
med1	ncor2	ENSORLP00000043584	ENSORLP00000017559	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 2.	0.686
ncor1	LOC101164305	ENSORLP00000015017	ENSORLP00000009000	Nuclear receptor corepressor 1.	Nuclear receptor subfamily 2, group E, member 3.	0.591
ncor1	med1	ENSORLP00000015017	ENSORLP00000043584	Nuclear receptor corepressor 1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.686