Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrrtm2Leucine rich repeat transmembrane neuronal 2. (547 aa)    
Predicted Functional Partners:
LOC101167491
Neurexin 1.
    
 0.898
LOC101169749
Uncharacterized protein.
    
 0.886
nrxn1
Neurexin 1.
    
 0.731
TMEM38B
Transmembrane protein 38B.
    
   0.666
zdhhc22
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
  
 0.624
ctnna2
Catenin (cadherin-associated protein), alpha 2.
    
 0.618
reep1
Receptor expression-enhancing protein.
      
 0.618
nlgn1
Neuroligin 1.
   
 
 0.615
hacd4
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
      
 0.606
etf1
Eukaryotic translation termination factor 1b.
      
 0.592
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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