STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101173499Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (491 aa)    
Predicted Functional Partners:
ch25h
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.986
LOC101168135
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 0.973
LOC101156734
Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family.
   
 0.973
LOC101157212
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
   
 0.973
LOC101157865
Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family.
   
 0.973
LOC105356506
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
   
 0.972
3bhsd
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 0.972
LOC101172816
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
   
 0.972
LOC101160538
Si:ch211-113j14.1; Belongs to the cytochrome P450 family.
  
  
 0.956
cyp11a
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
  
0.947
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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