Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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nubp2Cytosolic Fe-S cluster assembly factor nubp2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (271 aa)    
Predicted Functional Partners:
ciao3
Nuclear prelamin A recognition factor-like; Belongs to the NARF family.
   
 0.801
narf
Nuclear prelamin A recognition factor; Belongs to the NARF family.
   
 0.801
ciapin1
Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]
   
 0.792
abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7.
    
 0.721
ciao1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family.
 
 
 0.684
asmtl
Acetylserotonin O-methyltransferase-like.
  
   0.682
ndufs2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
     
 0.659
trarg1
Trafficking regulator of GLUT4 (SLC2A4) 1a.
    
 
 0.652
ndufs3
NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family.
     
 0.625
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component.
   
 0.614
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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