Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tbcdTubulin folding cofactor D. (1195 aa)    
Predicted Functional Partners:
Tbcc
Tubulin folding cofactor C.
    
 0.991
arl2
ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.
    
 0.986
tbce
Tubulin folding cofactor E.
    
 0.975
tbcb
Tubulin folding cofactor B.
    
 0.962
tbca
Tubulin-specific chaperone A; Belongs to the TBCA family.
    
 0.961
pfdn4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
    
 
 0.883
mad1l1
Mitotic arrest deficient 1 like 1.
   
 
 0.882
mad2l1
HORMA domain-containing protein.
    
 
 0.869
rp2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
    
 0.833
pfdn5
Prefoldin 5.
    
 
 0.775
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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