Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdia4Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (640 aa)    
Predicted Functional Partners:
LOC101167922
Endoplasmic reticulum oxidoreductase alpha.
   
 0.978
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.978
hspa5
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.971
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.945
LOC101160304
Calreticulin.
   
 0.922
LOC101162115
Calreticulin.
   
 0.922
LOC101169735
Calreticulin.
   
 0.922
tapbp
Uncharacterized protein.
    
 0.894
rpa2
Replication protein A2.
    
 0.863
ppib
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.848
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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