Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
herc3HECT and RLD domain containing E3 ubiquitin protein ligase 3. (1047 aa)    
Predicted Functional Partners:
LOC101161054
HECT domain-containing protein.
  
  
 
0.908
ube2l3
Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.757
psmb2
Proteasome subunit beta.
    
 
 0.737
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.652
rps27a
Ribosomal protein S27a.
    
 0.633
rsad2
Radical S-adenosyl methionine domain containing 2.
   
 
 0.617
slc45a2
Uncharacterized protein.
      
 0.580
LOC101158291
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.576
ubc
Ubiquitin B.
   
 0.543
LOC101158892
Interferon regulatory factor 3.
   
 0.543
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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