Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101171699Matrix metallopeptidase 14a (membrane-inserted). (570 aa)    
Predicted Functional Partners:
mmp2
Uncharacterized protein.
  
0.939
mmp14
ZnMc domain-containing protein.
  
  
 
0.901
timp-2b
Tissue inhibitor of metalloproteinase-2b.
   
 0.739
timp3
NTR domain-containing protein.
   
 0.707
timp2
Tissue inhibitor of metalloproteinase-2a.
   
 0.688
creld1
Cysteine-rich with EGF-like domains 1b.
      
 0.509
LOC101160439
Ceramide synthase 2b.
      
 0.503
noxo1
NADPH oxidase organizer 1a.
   
  
 0.497
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 2.
    
 0.497
nox5
NADPH oxidase, EF-hand calcium binding domain 5.
      
 0.493
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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