Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)    
Predicted Functional Partners:
LOC100125499
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.997
pmvk
Phosphomevalonate kinase.
   
 0.995
mvd
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
 
 
 0.993
LOC101166888
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.992
hmgcs1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.917
fdps
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
  
 0.885
idi1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.818
acat2
Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.802
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
  
  
 0.790
acaa1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.785
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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