Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccar1Cell division cycle and apoptosis regulator 1. (542 aa)    
Predicted Functional Partners:
u2af2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 0.961
zyx
Uncharacterized protein.
    
   0.927
prpf40a
PRP40 pre-mRNA processing factor 40 homolog A.
   
  0.920
brd7
Bromodomain containing 7.
   
  
 0.863
TCERG1
Transcription elongation regulator 1.
   
 
  0.821
ca7
Carbonic anhydrase VII; Belongs to the alpha-carbonic anhydrase family.
    
 
 0.776
srrt
Serrate RNA effector molecule homolog (Arabidopsis).
   
 
 0.770
ca10
Carbonic anhydrase Xa; Belongs to the alpha-carbonic anhydrase family.
    
 
 0.761
sirt5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
    
 0.725
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 0.725
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.