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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101155291Signal-induced proliferation-associated 1. (1034 aa)    
Predicted Functional Partners:
LOC101175047
Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
      
 0.851
H2LE95_ORYLA
Dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive).
   
  
 0.831
LOC101156270
Uncharacterized protein.
     
 0.598
wdr27
Uncharacterized protein.
 
  
 
 0.580
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.573
smoc2
SPARC related modular calcium binding 2.
      
 0.571
LOC101158728
V-rel avian reticuloendotheliosis viral oncogene homolog A.
      
 0.560
LOC101174851
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.545
RAP2B
RAP2B, member of RAS oncogene family.
    
 0.538
RAP2A
Uncharacterized protein.
    
 0.538
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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