Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101157602Dickkopf WNT signaling pathway inhibitor 3a. (266 aa)    
Predicted Functional Partners:
LOC101172518
Dickkopf WNT signaling pathway inhibitor 1a.
      
 0.777
dkk2
Dickkopf WNT signaling pathway inhibitor 2.
      
 0.683
wnt6
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.600
ENSORLP00000042326
Dickkopf_N domain-containing protein.
      
 0.535
LOC101174785
TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]
    
 0.529
psmd7
Proteasome 26S subunit, non-ATPase 7.
     
 0.525
LOC101163175
Homer scaffold protein 1b.
      
 0.501
kremen1
Kringle containing transmembrane protein 1.
    
 0.474
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 
 0.471
mical2
Microtubule associated monooxygenase, calponin and LIM domain containing 2a.
      
 0.464
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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