STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101157602Dickkopf WNT signaling pathway inhibitor 3a. (266 aa)    
Predicted Functional Partners:
LOC101174785
TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]
   
 0.566
LOC101163175
Homer scaffold protein 1b.
      
 0.563
usp47
Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.
      
 0.558
CLEC3A
C-type lectin domain family 3 member A.
   
  
 0.558
LOC101170511
Nuclear factor of activated T cells 5a.
      
 0.558
mical2
Microtubule associated monooxygenase, calponin and LIM domain containing 2a.
      
 0.558
kremen1
Kringle containing transmembrane protein 1.
    
 0.522
LOC101172518
Dickkopf WNT signaling pathway inhibitor 1a.
      
 0.485
dab2
DAB adaptor protein 2.
   
 0.424
cd59
CD59 molecule (CD59 blood group).
   
 0.408
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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