Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
zfand4Zinc finger, AN1-type domain 4. (716 aa)    
Predicted Functional Partners:
trip12
Thyroid hormone receptor interactor 12.
   
 0.954
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.939
H2M970_ORYLA
Ubiquitin-like domain-containing protein.
   
 0.939
rps27a
Ribosomal protein S27a.
   
 0.931
ubxn7
UBX domain protein 7.
    
 0.892
rtf2
Replication termination factor 2.
      
 0.864
psmc3
Proteasome 26S subunit ATPase 3; Belongs to the AAA ATPase family.
   
 0.863
fau
40S ribosomal protein S30.
   
 0.863
psmb2
Proteasome subunit beta.
   
 0.860
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 0.859
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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