Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1365 aa)    
Predicted Functional Partners:
polb
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
 0.965
fbxw11
F-box and WD repeat domain containing 11a.
    
 
 0.917
ubc
Ubiquitin B.
    
 
 0.750
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.728
otud6b
OTU domain containing 6B.
      
 0.698
josd2
Josephin domain containing 2.
      
 0.678
trip12
Thyroid hormone receptor interactor 12.
   
  
 0.652
zranb1
Zinc finger, RAN-binding domain containing 1a.
   
 
 0.650
LOC101168392
Zinc finger, RAN-binding domain containing 1b.
   
 
 0.650
poll
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
    
 0.637
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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