Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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drd2Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family. (467 aa)    
Predicted Functional Partners:
LOC105358374
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
 0.949
gnai3
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]
    
 0.949
LOC101157265
Uncharacterized protein.
    
 0.949
gnai2
Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity).
    
 0.949
LOC101158355
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
    
 0.949
H2L8B2_ORYLA
Dopamine receptor D1b; Belongs to the G-protein coupled receptor 1 family.
   
0.932
LOC101169046
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
0.932
H2LMC1_ORYLA
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
  
  
 
0.904
LOC101171193
Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family.
  
  
 
0.902
LOC101168199
WD_REPEATS_REGION domain-containing protein.
    
  0.879
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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