Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arhgap10Rho GTPase activating protein 10. (767 aa)    
Predicted Functional Partners:
c2cd2
C2 calcium dependent domain containing 2.
    
   0.962
LOC101168921
Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
    
 0.918
LOC101169951
Uncharacterized protein.
    
 0.918
LOC101173070
Uncharacterized protein.
    
 0.918
LOC101155523
Uncharacterized protein.
    
 0.918
LOC101155777
Uncharacterized protein.
    
 0.918
LOC101171502
Uncharacterized protein.
     
  0.900
ctnnb1
Catenin (cadherin-associated protein), beta 1.
     
  0.900
Brk1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 0.843
LOC101169249
Non-specific serine/threonine protein kinase.
    
 0.770
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.