Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MLANAUncharacterized protein. (120 aa)    
Predicted Functional Partners:
TYR
Tyrosinase.
   
  
 0.974
pmel
Premelanosome protein a.
   
  
 0.955
gpr143
G protein-coupled receptor 143.
   
 
 0.857
tyrp1
Tyrosinase related protein 1.
   
  
 0.832
LOC101161292
Tyrosinase-related protein 1b.
   
  
 0.783
slc24a5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.753
dct
Dopachrome tautomerase.
      
 0.708
tyr
Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.
      
 0.685
slc45a2
Uncharacterized protein.
   
  
 0.652
rasef
RAS and EF-hand domain containing.
      
 0.645
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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