Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
txnThioredoxin; Belongs to the thioredoxin family. (106 aa)    
Predicted Functional Partners:
txnip
Thioredoxin interacting protein.
    
 0.998
LOC101163138
Arrestin_C domain-containing protein.
    
 0.997
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.988
LOC101169850
Thioredoxin reductase 3.
  
 0.984
txn2
Thioredoxin 2.
  
0.983
LOC101167985
Si:ch211-1i11.3.
    
 0.962
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.962
prdx2
Peroxiredoxin 2.
  
 0.955
prdx3
Peroxiredoxin 3.
  
 0.954
LOC101175597
Peroxiredoxin 1.
  
 0.954
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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