STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (946 aa)    
Predicted Functional Partners:
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.984
LOC101169984
Receptor protein-tyrosine kinase.
    
 0.977
egfr
Receptor protein-tyrosine kinase.
    
 0.977
rapgef1
Uncharacterized protein.
   
 0.963
LOC101158464
Rap guanine nucleotide exchange factor (GEF) 1b.
   
 0.963
SH2B2
SH2B adaptor protein 2.
    
 0.962
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
  
 
 
0.949
sh3kbp1
SH3-domain kinase binding protein 1.
    
 0.943
LOC101168764
Tyrosine-protein kinase receptor.
    
 0.928
LOC101166254
Tyrosine-protein kinase receptor.
    
 0.928
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.