Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam43aFamily with sequence similarity 43 member A. (355 aa)    
Predicted Functional Partners:
plekhf2
Pleckstrin homology domain containing, family F (with FYVE domain) member 2.
      
 0.741
neurl1b
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.703
LOC101162479
TOX high mobility group box family member 4 a.
      
 0.609
ppp2r5b
Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.
    
   0.601
lsg1
Large 60S subunit nuclear export GTPase 1.
      
 0.568
scly
Selenocysteine lyase.
      
 0.519
nop53
Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.
      
 0.493
tox4
TOX high mobility group box family member 4 b.
      
 0.487
phf5a
PHD finger protein 5A.
      
 0.483
snx29
Sorting nexin 29.
      
 0.462
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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