Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nkx2-3NK2 homeobox 3. (341 aa)    
Predicted Functional Partners:
hand2
Heart and neural crest derivatives expressed 2.
    
 0.615
LOC101155601
CCAAT enhancer binding protein beta.
    
 
 0.571
poll
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
      
 0.520
wdr11
WD repeat domain 11.
      
 0.502
LOC100125524
Forkhead box N1.
    
 0.455
ubtf
Upstream binding transcription factor.
      
 0.445
LOC111949113
Upstream binding transcription factor, like.
      
 0.445
gata3
Uncharacterized protein.
   
 0.410
traf3ip1
TNF receptor-associated factor 3 interacting protein 1.
      
 0.405
foxf1
Forkhead box F1.
    
 0.401
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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