rfx3 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rfx3

Regulatory factor X, 3 (influences HLA class II expression). (754 aa)

Predicted Functional Partners:

atr

0.766

foxj1

0.655

chek2

0.644

ARVCF

0.518

spag6

0.511

rfxap

0.507

dpcd

0.473

e4f1

0.471

smarca4

0.454

creb5

0.434

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARVCF	rfx3	ENSORLP00000040441	ENSORLP00000009706	ARVCF delta catenin family member b.	Regulatory factor X, 3 (influences HLA class II expression).	0.518
atr	chek2	ENSORLP00000015251	ENSORLP00000032936	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint kinase 2.	0.955
atr	rfx3	ENSORLP00000015251	ENSORLP00000009706	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Regulatory factor X, 3 (influences HLA class II expression).	0.766
chek2	atr	ENSORLP00000032936	ENSORLP00000015251	Checkpoint kinase 2.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.955
chek2	rfx3	ENSORLP00000032936	ENSORLP00000009706	Checkpoint kinase 2.	Regulatory factor X, 3 (influences HLA class II expression).	0.644
creb5	rfx3	ENSORLP00000009415	ENSORLP00000009706	cAMP responsive element binding protein 5b.	Regulatory factor X, 3 (influences HLA class II expression).	0.434
dpcd	foxj1	ENSORLP00000031120	ENSORLP00000036891	Deleted in primary ciliary dyskinesia homolog (mouse).	Fork-head domain-containing protein.	0.534
dpcd	rfx3	ENSORLP00000031120	ENSORLP00000009706	Deleted in primary ciliary dyskinesia homolog (mouse).	Regulatory factor X, 3 (influences HLA class II expression).	0.473
dpcd	spag6	ENSORLP00000031120	ENSORLP00000009038	Deleted in primary ciliary dyskinesia homolog (mouse).	Sperm associated antigen 6.	0.615
e4f1	rfx3	ENSORLP00000011493	ENSORLP00000009706	E4F transcription factor 1.	Regulatory factor X, 3 (influences HLA class II expression).	0.471
e4f1	smarca4	ENSORLP00000011493	ENSORLP00000019353	E4F transcription factor 1.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a.	0.480
e4f1	spag6	ENSORLP00000011493	ENSORLP00000009038	E4F transcription factor 1.	Sperm associated antigen 6.	0.491
foxj1	dpcd	ENSORLP00000036891	ENSORLP00000031120	Fork-head domain-containing protein.	Deleted in primary ciliary dyskinesia homolog (mouse).	0.534
foxj1	rfx3	ENSORLP00000036891	ENSORLP00000009706	Fork-head domain-containing protein.	Regulatory factor X, 3 (influences HLA class II expression).	0.655
foxj1	spag6	ENSORLP00000036891	ENSORLP00000009038	Fork-head domain-containing protein.	Sperm associated antigen 6.	0.409
rfx3	ARVCF	ENSORLP00000009706	ENSORLP00000040441	Regulatory factor X, 3 (influences HLA class II expression).	ARVCF delta catenin family member b.	0.518
rfx3	atr	ENSORLP00000009706	ENSORLP00000015251	Regulatory factor X, 3 (influences HLA class II expression).	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.766
rfx3	chek2	ENSORLP00000009706	ENSORLP00000032936	Regulatory factor X, 3 (influences HLA class II expression).	Checkpoint kinase 2.	0.644
rfx3	creb5	ENSORLP00000009706	ENSORLP00000009415	Regulatory factor X, 3 (influences HLA class II expression).	cAMP responsive element binding protein 5b.	0.434
rfx3	dpcd	ENSORLP00000009706	ENSORLP00000031120	Regulatory factor X, 3 (influences HLA class II expression).	Deleted in primary ciliary dyskinesia homolog (mouse).	0.473