Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101172817Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1119 aa)    
Predicted Functional Partners:
suds3
SDS3 homolog, SIN3A corepressor complex component.
    
 0.844
LOC101164496
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
    
 0.677
rce1
Ras converting CAAX endopeptidase 1a.
     
 0.666
ENSORLP00000043660
Uncharacterized protein.
     
 0.666
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
    
  0.659
fau
40S ribosomal protein S30.
    
 0.643
usp30
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.642
cdc25b
Rhodanese domain-containing protein.
    
 0.614
ifih1
Interferon induced with helicase C domain 1.
     
 0.595
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
     
0.593
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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