Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tln2Talin 2b. (2405 aa)    
Predicted Functional Partners:
vcl
Vinculin b.
   
 0.996
LOC101172101
Vinculin a.
   
 0.996
itgb5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.959
itgb1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.957
LOC101168465
Integrin beta; Belongs to the integrin beta chain family.
   
 0.956
itgb6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.955
itgb3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.953
itgb8
Integrin beta; Belongs to the integrin beta chain family.
   
 0.948
itgb4
Integrin beta.
   
 0.929
LOC101164919
Uncharacterized protein; Belongs to the peptidase C2 family.
   
 0.914
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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