Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
p2rx2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)    
Predicted Functional Partners:
p2rx3
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.669
p2rx4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.664
LOC101166974
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.588
LOC101165456
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.588
P2RY6
Pyrimidinergic receptor P2Y6.
      
 0.586
LOC101170891
Tripartite motif containing 105.
      
 0.580
tbc1d24
TBC1 domain family, member 24.
      
 0.563
p2rx1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.560
LOC101173001
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.560
P2RY4
Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.
      
 0.555
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.