Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISL2ISL LIM homeobox 2a. (358 aa)    
Predicted Functional Partners:
LOC101162780
LIM domain binding 1a.
    
 0.818
ldb2
LIM domain binding 2a.
    
 0.818
LOC101158085
LIM-domain binding 1b.
    
 0.818
lhx3
Uncharacterized protein.
   
 0.801
lhx4
LIM homeobox 4.
   
 0.801
nkx2-5
Homeobox domain-containing protein.
    
 0.747
tbx20
T-box transcription factor 20.
   
 0.718
znf511
Zinc finger protein 511.
    
   0.655
idi1
Isopentenyl-diphosphate delta isomerase 1.
    
   0.618
LOC101169513
LIM domain only 4a.
    
   0.602
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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