Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101158465Melanopsin. (408 aa)    
Predicted Functional Partners:
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.516
trarg1
Trafficking regulator of GLUT4 (SLC2A4) 1a.
    
 0.504
LOC101168199
WD_REPEATS_REGION domain-containing protein.
    
 0.487
LOC101175500
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
 0.487
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
 0.487
ol-gb1
WD_REPEATS_REGION domain-containing protein.
    
 0.487
aamp
Angio-associated, migratory cell protein.
     
 0.481
LOC101168134
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.477
LOC101173389
Cryptochrome circadian regulator 2.
    
 
 0.468
LOC111946430
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.462
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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