Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
olgc5Guanylate cyclase. (1151 aa)    
Predicted Functional Partners:
nppc
C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
    
 0.733
unc93a
Unc-93 homolog A.
      
 0.547
rd3
Retinal degeneration 3, GUCY2D regulator.
    
 
 0.522
LOC101172917
Guanylate cyclase activator 1C.
   
 0.521
guca1a
Guanylate cyclase activating protein 1.
   
 0.511
helz
Helicase with zinc finger.
      
 0.509
RDH8
Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.506
LOC101159879
Uncharacterized protein.
   
 0.505
LOC101174207
Aryl hydrocarbon receptor interacting protein-like 1.
   
  
 0.504
LOC101168199
WD_REPEATS_REGION domain-containing protein.
    
 0.502
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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