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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zfhx3Zinc finger homeobox 3. (3858 aa)    
Predicted Functional Partners:
csmd3
CUB and Sushi multiple domains 3a.
      
 0.813
CSMD1
CUB and Sushi multiple domains 1.
      
 0.813
fancc
FA complementation group C.
      
 0.601
LOC101157631
Transforming growth factor beta; Belongs to the TGF-beta family.
    
  0.597
LOC101160370
Runt-related transcription factor.
     
 0.595
runx2
Runt-related transcription factor.
     
 0.594
LOC101173202
RUNX family transcription factor 1.
     
 0.594
LOC101167336
Runt domain-containing protein.
     
 0.575
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
      
 0.544
med12
Mediator complex subunit 12.
      
 0.426
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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