Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101162283Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)    
Predicted Functional Partners:
card11
Caspase recruitment domain family, member 11.
   
 0.910
LOC101172398
ELAV-like protein; Belongs to the RRM elav family.
    
  0.821
LOC101170313
ELAV-like protein; Belongs to the RRM elav family.
    
  0.821
pdpk1
3-phosphoinositide dependent protein kinase 1b.
    
 0.766
ncf1
Neutrophil cytosolic factor 1.
   
 0.677
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.662
LOC101171857
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.662
card9
Caspase recruitment domain family, member 9.
    
 0.651
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
    
 
 0.650
tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
    
 0.641
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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