Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (570 aa)    
Predicted Functional Partners:
mettl14
Methyltransferase like 14; Belongs to the MT-A70-like family.
   
  
 0.911
LOC101162819
Zinc finger CCCH-type containing 13.
      
 0.888
rbm15
RNA binding motif protein 15.
      
 0.886
wtap
WT1 associated protein.
      
 0.885
alkbh5
AlkB homolog 5, RNA demethylase.
   
  
 0.855
mepce
Methylphosphate capping enzyme.
    
 
 0.844
virma
Vir like m6A methyltransferase associated.
    
 
 0.790
bcdin3d
BCDIN3 domain containing.
    
 
 0.789
mettl5
Methyltransferase like 5.
      
 0.767
zcchc4
Zinc finger, CCHC domain containing 4.
   
  
 0.763
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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