Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
LOC101162521Ubiquitin-like modifier activating enzyme 3. (462 aa)    
Predicted Functional Partners:
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
   
 0.993
ENSORLP00000027520
Ubiquitin-like domain-containing protein.
    
 0.937
ENSORLP00000045836
Ubiquitin-like domain-containing protein.
    
 0.937
cul1
Cullin 1b; Belongs to the cullin family.
   
 0.923
ube2m
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.918
ube2f
Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.918
UBA3
Ubiquitin like modifier activating enzyme 3.
  
  
 
0.901
LOC101163973
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.839
ube2h
Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.839
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.835
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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