Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100049265Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (265 aa)    
Predicted Functional Partners:
LOC101166883
X-linked inhibitor of apoptosis.
   
 0.984
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
0.983
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 0.980
casp8
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.968
LOC101172600
Baculoviral IAP repeat containing 2.
   
 0.967
LOC101155061
Baculoviral IAP repeat containing 5a.
   
 0.963
gsdme
Gasdermin Eb.
    
 0.963
LOC101175466
Uncharacterized protein.
   
  0.956
LOC101155570
Serine/threonine kinase 3 (STE20 homolog, yeast).
   
  0.956
LOC101168459
Baculoviral IAP repeat containing 5b.
   
 0.950
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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