Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
r3hdm4R3H domain containing 4. (255 aa)    
Predicted Functional Partners:
ERG28
Ergosterol biosynthesis 28 homolog.
   
 
 0.712
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.671
LOC101157258
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.671
ndufaf6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
   
 
 0.610
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
   
 
 0.610
faxdc2
Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family.
   
 0.485
LOC101168135
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 0.485
LOC101156734
Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family.
   
 0.485
msmo1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.485
LOC101157212
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
   
 0.485
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.