STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr3Toll-like receptor 3. (917 aa)    
Predicted Functional Partners:
LOC101154981
Toll-like receptor adaptor molecule 1.
   
 0.954
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.916
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.858
unc93b1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.852
LOC101158892
Interferon regulatory factor 3.
   
 
 0.755
tradd
Tnfrsf1a-associated via death domain.
    
 
 0.683
traf3
TNF receptor-associated factor.
   
 0.668
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.667
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.635
il10
Interleukin 10.
   
 
 0.626
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.