Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tlr3Toll-like receptor 3. (917 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.979
LOC101154981
Toll-like receptor adaptor molecule 1.
    
 0.956
LOC101158892
Interferon regulatory factor 3.
    
 0.933
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.918
unc93b1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.807
tbk1
TANK-binding kinase 1.
   
 0.803
il10
Interleukin 10.
   
 
 0.792
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.767
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.766
ifih1
Interferon induced with helicase C domain 1.
   
 
 0.754
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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