Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101167472Connector enhancer of kinase suppressor of Ras 2b. (956 aa)    
Predicted Functional Partners:
SAMD12
Sterile alpha motif domain containing 12.
    
 0.777
ksr2
Kinase suppressor of ras 2.
    
 0.761
ksr1
Kinase suppressor of ras 1a.
    
 0.761
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.722
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.722
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.722
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
 0.646
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
    
 0.646
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
    
 0.646
LOC101156149
Uncharacterized protein.
    
 0.533
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]