Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COL6A3Collagen type VI alpha 3 chain. (2705 aa)    
Predicted Functional Partners:
LOC101158275
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family.
    
 0.799
itgb3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.792
itga2
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.
    
0.786
itgb8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.782
LOC101168465
Integrin beta; Belongs to the integrin beta chain family.
    
 0.734
itgb5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.734
itga11
Integrin, alpha 11a; Belongs to the integrin alpha chain family.
    
0.732
itga1
Integrin, alpha 1; Belongs to the integrin alpha chain family.
    
0.732
itga10
Integrin, alpha 10; Belongs to the integrin alpha chain family.
    
0.732
LOC101169424
VWFA domain-containing protein; Belongs to the integrin alpha chain family.
    
0.732
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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