Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
itm2bIntegral membrane protein 2Bb. (258 aa)    
Predicted Functional Partners:
LOC101172288
Amyloid beta (A4) precursor protein b.
   
 0.814
APP
Amyloid beta precursor protein.
   
 0.814
aplp2
Amyloid beta (A4) precursor-like protein 2.
   
 0.741
LOC101173159
Motilin receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.696
cdadc1
Cytidine and dCMP deaminase domain containing 1.
      
 0.694
copa
Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
    
 
 0.679
LOC101173369
Junction plakoglobin a.
   
 
 0.661
tmem59
Transmembrane protein 59.
   
 
 0.661
gnb1l
Guanine nucleotide binding protein (G protein), beta polypeptide 1-like.
      
 0.658
ndufb6
NADH:ubiquinone oxidoreductase subunit B.
    
 
 0.654
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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