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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itm2bIntegral membrane protein 2Bb. (258 aa)    
Predicted Functional Partners:
LOC101167635
Euchromatic histone-lysine N-methyltransferase 1b.
      
 0.582
copa
Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
      
 0.574
ptpn1
Tyrosine-protein phosphatase non-receptor type.
   
  
 0.562
LOC101174914
Uncharacterized protein.
   
 
 0.553
mgst3
Uncharacterized protein.
    
 
 0.545
psmc5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
      
 0.539
irf2bp2
Interferon regulatory factor 2 binding protein 2.
      
 0.539
LOC101170562
Uncharacterized protein.
      
 0.535
LOC101161354
Microsomal glutathione S-transferase 3b.
    
 
 0.535
cdk8
Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.
      
 0.532
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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