Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101163844Uncharacterized protein. (311 aa)    
Predicted Functional Partners:
notch1
Notch receptor 1b.
    
 0.702
LOC101171596
Notch receptor 1a.
    
 0.702
pggt1b
Protein geranylgeranyltransferase type I, beta subunit.
    
 
 0.666
LOC101162450
Notch receptor 3.
    
 0.599
ist1
IST1 factor associated with ESCRT-III.
    
   0.598
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.568
creb3l1
cAMP responsive element binding protein 3-like 1.
      
 0.562
HES2
Hes family bHLH transcription factor 2, tandem duplicate 1.
    
 0.551
nkx1-1
NK1 transcription factor related 2-like,b.
    
 
 0.525
LOC101169577
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.515
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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