Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
PNMTPhenylethanolamine N-methyltransferase. (148 aa)    
Predicted Functional Partners:
dbh
Dopamine beta-hydroxylase (dopamine beta-monooxygenase).
   
 
 0.956
comt
Catechol-O-methyltransferase b.
     
 0.938
LOC101165493
Transmembrane O-methyltransferase.
     
 0.936
maob
Amine oxidase.
     
 0.921
LOC101175668
Amine oxidase.
     
 0.921
pnmt
Uncharacterized protein.
 
      0.899
ENSORLP00000036355
Uncharacterized protein.
      
 0.659
hsf2bp
Heat shock transcription factor 2 binding protein.
      
 0.654
sp1
Sp1 transcription factor.
      
 0.621
th
Tyrosine hydroxylase 1.
      
 0.620
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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