STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR1WD repeat domain 1. (605 aa)    
Predicted Functional Partners:
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.931
cfl1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 
 0.792
LOC101159957
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 
 0.792
LOC101155832
Uncharacterized protein; Belongs to the actin family.
   
 0.788
LOC101158395
Actin related protein 3; Belongs to the actin family.
   
 0.788
LOC101162164
Actin related protein 3B; Belongs to the actin family.
   
 0.788
LOC101164501
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.750
cap1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.744
cap2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.744
ACTA1
Actin alpha 1, skeletal muscle.
   
 0.714
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.