STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UPF1UPF1 RNA helicase and ATPase. (1101 aa)    
Predicted Functional Partners:
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 0.999
Smg1
SMG1_N domain-containing protein.
   
 0.994
upf3b
UPF3B regulator of nonsense mediated mRNA decay.
    
 0.993
LOC101167578
UPF3A regulator of nonsense mediated mRNA decay.
    
 0.993
rnps1
RNA binding protein S1, serine-rich domain.
    
 0.987
casc3
Casc3 exon junction complex subunit.
    
 0.979
smg6
SMG6 nonsense mediated mRNA decay factor.
   
 0.978
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.978
smg5
SMG5 nonsense mediated mRNA decay factor.
   
 0.969
ALYREF
Aly/REF export factor.
   
 
 0.964
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.