Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2LWX7_ORYLASerine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (326 aa)    
Predicted Functional Partners:
LOC101161023
Si:ch211-63o20.7; Belongs to the protein kinase superfamily.
  
 
 0.553
rptor
Regulatory associated protein of MTOR, complex 1.
    
 0.543
LOC101172961
Serine/threonine kinase 35; Belongs to the protein kinase superfamily.
  
 
 0.533
pdik1l
PDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily.
  
 
 0.520
ENSORLP00000032087
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
  0.472
cetn3
Centrin 3.
    
 0.462
LOC101170769
Centrin, EF-hand protein, 2.
    
 0.462
crppa
CDP-L-ribitol pyrophosphorylase A.
    
 0.462
H2MI39_ORYLA
Neurotrophic tyrosine kinase, receptor, type 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family.
  
 
  0.445
LOC101165981
Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.
  
 
 0.437
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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