Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sgk3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (492 aa)    
Predicted Functional Partners:
pdpk1
3-phosphoinositide dependent protein kinase 1b.
    
0.985
vcpip1
Valosin containing protein (p97)/p47 complex interacting protein 1.
    
 
 0.840
foxo3
Forkhead box O5.
   
 0.754
rps6
Ribosomal protein S6.
    
 0.749
foxo1
Fork-head domain-containing protein.
    
 0.748
LOC110015734
Forkhead box O4.
    
 0.748
mapkap1
MAPK associated protein 1.
    
 0.744
rptor
Regulatory associated protein of MTOR, complex 1.
    
 0.741
rictor
RPTOR independent companion of MTOR, complex 2 a.
    
 0.740
LOC101164740
Fork-head domain-containing protein.
    
 0.737
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.