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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf2Interferon regulatory factor. (320 aa)    
Predicted Functional Partners:
LOC101163430
Interferon regulatory factor.
  
0.803
c-fos
BZIP domain-containing protein.
    
 
 0.593
LOC101171800
IRF-2BP1_2 domain-containing protein.
   
 
 0.579
ENSORLP00000033146
Interferon regulatory factor 2 binding protein 1.
   
 
 0.579
irf2bp2
Interferon regulatory factor 2 binding protein 2.
   
 
 0.579
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.558
cd82
Tetraspanin.
      
 0.515
LOC111948510
Interferon regulatory factor 2 binding protein 1.
   
 
 0.515
batf
Basic leucine zipper transcription factor, ATF-like.
   
 
 0.479
mdm2
MDM2 proto-oncogene.
    
 0.466
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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