Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KDELR2ER lumen protein-retaining receptor. (271 aa)    
Predicted Functional Partners:
tmed10
Transmembrane p24 trafficking protein 10.
   
 0.890
surf4
Surfeit 4.
   
 0.865
copb1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.822
LOC101161906
Transmembrane p24 trafficking protein 2.
   
 0.786
trip12
Thyroid hormone receptor interactor 12.
    
   0.760
arfgap1
ADP-ribosylation factor GTPase activating protein 1.
    
 0.751
yif1a
Yip1 interacting factor homolog A (S. cerevisiae).
   
 
 0.734
arcn1
Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 
 0.731
gbf1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 0.720
ykt6
YKT6 v-SNARE homolog (S. cerevisiae); Belongs to the synaptobrevin family.
   
 
 0.716
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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