STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (765 aa)    
Predicted Functional Partners:
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
      
 0.793
pomc
Proopiomelanocortin.
    
 0.741
LOC101164777
Uncharacterized protein.
    
 0.741
LOC100125446
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.729
LOC101172253
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.729
bsnd
Uncharacterized protein.
      
 0.712
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.708
cpe
Carboxypeptidase E.
   
  
 0.605
LOC101160750
Protein kinase domain-containing protein.
      
 0.592
rfx6
Regulatory factor X, 6.
      
 0.575
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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