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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101158107Rho guanine nucleotide exchange factor (GEF) 3, like. (495 aa)    
Predicted Functional Partners:
rrad
Ras-related associated with diabetes.
    
 0.839
akap12
A kinase (PRKA) anchor protein 12b.
   
  
 0.801
LOC101156944
RAS protein activator like 3.
   
  
 0.732
LOC101155194
Uncharacterized protein.
    
 0.514
RND1
Rho family GTPase 1.
    
 0.514
RHOB
Ras homolog family member B.
    
 0.514
LOC101173444
Uncharacterized protein.
    
 0.514
LOC101158607
Uncharacterized protein.
    
 0.514
LOC101168783
Rho family GTPase 1b.
    
 0.514
LOC101160539
Uncharacterized protein.
    
 0.514
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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