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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOSMOUncharacterized protein. (167 aa)    
Predicted Functional Partners:
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.910
LOC101154810
Uncharacterized protein.
  
  
 
0.901
rnf157
Ring finger protein 157.
      
 0.507
plod2
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2.
   
 0.424
ogfod2
2-oxoglutarate and iron-dependent oxygenase domain containing 2.
   
 0.424
plod1
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.
   
 0.424
Plod3
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.
   
 0.424
ENSORLP00000042136
Uncharacterized protein.
   
 0.424
setd5
SET domain containing 5.
      
 0.400
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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