Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ngly1N-glycanase 1. (651 aa)    
Predicted Functional Partners:
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.989
psmc1
Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.
   
 0.988
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
    
 0.987
ubxn1
UBX domain protein 1.
    
 0.973
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
    
 0.966
rad23a
RAD23 homolog A, nucleotide excision repair protein a.
    
 0.966
spata5l1
Spermatogenesis associated 5-like 1.
    
 0.919
engase
Endo-beta-N-acetylglucosaminidase.
   
  
 0.897
nsfl1c
NSFL1 (p97) cofactor (p47).
    
 
 0.876
katnal2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
    
 0.867
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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